Camonsertib
Camonsertib (RP-3500) is a selective, orally active ATR kinase inhibitor (ATRi) with an IC50: 1.00 nM in biochemical assays and exhibits potent antitumour effects. Camonsertib is 30 times more selective for ATR than mTOR (IC50: 120 nM) and is a more active inhibitor of ATM, DNA-PK and PI3Kα kinases. PK and PI3Kα kinases.
| Catalog Number | T62083 |
| Alternative Name(s) | ATR inhibitor 4 , RP-3500 |
| Research Area | PI3K/Akt/mTOR signaling|||DNA Damage/DNA Repair |
| Molecular Formula | C21H26N6O3 |
| CAS# | 2417489-10-0 |
| Purity | 98.15% |
| SMILES | O[C@]1(C2=C3C(N(N=C3)C=4C=CNN4)=NC(=C2)N5[C@H](C)COCC5)C[C@]6(O[C@@](C1)(CC6)[H])[H] |
| Size | 1 mL |
| Supplier Page | https://www.targetmol.com/compound/rp-3500 |
| Additional Information | https://www.targetmol.com/datasheet/T62083 |