(+)-Macrosphelide A

(+)-Macrosphelide A is a fungal metabolite originally isolated from Microsphaeropsis. It inhibits adhesion of HL-60 human leukemia cells to human umbilical vein endothelial cells (HUVECs) in a concentration-dependent manner. It also inhibits the growth of SKOV3 ovarian cancer cells in a concentration-dependent manner. (+)-Macrosphelide A inhibits the growth of Gram-positive bacteria, including B. subtilis, M. luteus, B. thuringiensis, and S. aureus (MICs = 143, 143, 57, and 57 μg/ml, respectively), but not Gram-negative bacteria or fungi.

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Catalog Number	T37552
Molecular Formula	C16H22O8
CAS#	172923-77-2
SMILES	C[C@H]1CC(=O)O[C@@H](C)[C@H](O)\C=C\C(=O)O[C@@H](C)[C@H](O)\C=C\C(=O)O1 \|t:10,19\|
Size	1 mg
Supplier Page	https://www.targetmol.com/compound/(+)-macrosphelide_a
Additional Information	https://www.targetmol.com/datasheet/T37552