Paraformaldehyde-d2 is key precursors for many deuterium-labeled compounds that could be useful for multiple fields of research such as
For example, it could be used for mass spectrometry based quantification of highly homologous proteins. Such biomolecules usually have amino group, which upon reductive methylation could be converted to methyl groups having different but controlled isotope composition ( Yi-Min She, Michael Rosu-Myles, Lisa Walrond and Terry D. Cyr Proteomics 2012, 12, 369–379).