N,N-Dimethylformamide diethyl acetal

N,N-Dimethylformamide diethyl acetal undergoes Me3SiCl-mediated three-component coupling reaction with alkyne to yield 2,3,4,5-tetrasubstituted pyridine derivatives. N,N-Dimethylformamide diethyl acetal (DMF diethyl acetal) on reaction with butanol affords N,N-dimethylformamide dibutyl acetal. It participates in various alkylation, formylation, and aminomethylenation reactions. It has been synthesized from N,N-dialkyl(chloromethylene)ammonium chloride.

Catalog Number CBB1116038
Alternative Name(s) 1,1-Diethoxy-N,N-dimethylmethylamine; 1,1-Diethoxytrimethylamine
Molecular Formula (CH3)2NCH(OC2H5)2
CAS# 1188-33-6
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N,N-Dimethylformamide diethyl acetal

N,N-Dimethylformamide diethyl acetal undergoes Me3SiCl-mediated three-component coupling reaction with alkyne to yield 2,3,4,5-tetrasubstituted pyridine derivatives.

Catalog Number CBB1116039
Alternative Name(s) 1,1-Diethoxy-N,N-dimethylmethylamine; 1,1-Diethoxytrimethylamine
Molecular Formula (CH3)2NCH(OC2H5)2
CAS# 1188-33-6
Purity >95%
Inchi 1S/C7H17NO2/c1-5-9-7(8(3)4)10-6-2/h7H,5-6H2,1-4H3
Inchi Key BWKAYBPLDRWMCJ-UHFFFAOYSA-N
SMILES CCOC(OCC)N(C)C
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