18α-Glycyrrhetinic acid
18α-Glycyrrhetinic acid (18α-GA) is a bioactive triterpenoid found in licorice. It shows selective inhibition of 11-HSD1 (11-hydroxysteroid dehydrogenase 1). It also shows anti-proliferative and apoptotic effect on hepatic stellate cells (HSCs).
| Catalog Number | CBB1113704 |
| Alternative Name(s) | 18-Isoglycyrrhetinic acid; 18α-Glycyrrhetic acid; 3β-Hydroxy-11-oxo-18α,20β-olean-12-en-29-oic acid |
| Molecular Formula | C30H46O4 |
| CAS# | 1449-05-4 |
| Purity | >95% |
| Inchi | 1S/C30H46O4/c1-25(2)21-8-11-30(7)23(28(21,5)10-9-22(25)32)20(31)16-18-19-17-27(4,24(33)34)13-12-26(19,3)14-15-29(18,30)6/h16,19,21-23,32H,8-15,17H2,1-7H3,(H,33,34)/t19-,21+,22+,23-,26-,27+,28+,29-,30-/m1/s1 |
| Inchi Key | MPDGHEJMBKOTSU-PMTKVOBESA-N |
| SMILES | [H][C@]12C[C@](C)(CC[C@]1(C)CC[C@]3(C)C2=CC(=O)C4[C@@]5(C)CC[C@H](O)C(C)(C)[C@]5([H])CC[C@@]34C)C(O)=O |
| Size | Inquiry |
| Supplier Page | https://www.amerigoscientific.com/18-glycyrrhetinic-acid-item-113704.html |