p-Toluenesulfonylmethyl isocyanide

p-Toluenesulfonylmethyl isocyanide undergoes base-promoted 1,3-dipolar cycloaddition reaction with immobilized imines under microwave irradiation to yield 1,5-disubstituted imidazoles. It is a versatile synthon in organic chemistry, extensively used for the synthesis of heterocyclic compounds.

Catalog Number CBB1112145
Alternative Name(s) TosMIC; Tosylmethyl isocyanide; (p-Tolylsulfonyl)methyl isocyanide
Molecular Formula CH3C6H4SO2CH2NC
CAS# 36635-61-7
Purity >98%
Inchi 1S/C9H9NO2S/c1-8-3-5-9(6-4-8)13(11,12)7-10-2/h3-6H,7H2,1H3
Inchi Key CFOAUYCPAUGDFF-UHFFFAOYSA-N
SMILES Cc1ccc(cc1)S(=O)(=O)C[N+]#[C-]
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