TPP-1 (hydrochloride)
A peptide inhibitor of the PD-1-PD-L1 protein-protein interaction
| Catalog Number | 37410 |
| Alternative Name(s) | Targeting PD-L1 Peptide |
| Research Area | Adaptive Immunity|Cancer|Immunology|Immunology & Inflammation |
| Molecular Formula | C107H150N34O32S2 • HCl |
| Purity | ≥95% |
| Inchi | InChI=1S/C107H150N34O32S2.ClH/c1-53(125-94(161)70(33-54-19-23-59(146)24-20-54)131-93(160)68(27-28-82(110)148)127-85(151)44-121-89(156)63(109)46-142)88(155)137-78(49-145)100(167)132-71(34-55-21-25-60(147)26-22-55)95(162)135-74(37-58-41-115-52-124-58)98(165)140-80(51-175)102(169)134-73(36-57-40-119-65-14-5-3-12-62(57)65)97(164)139-79(50-174)101(168)133-72(35-56-39-118-64-13-4-2-11-61(56)64)96(163)129-67(17-9-31-117-107(113)114)92(159)136-75(38-87(153)154)104(171)141-32-10-18-81(141)103(170)123-45-86(152)126-66(16-8-30-116-106(111)112)91(158)138-76(47-143)90(157)122-42-83(149)120-43-84(150)128-77(48-144)99(166)130-69(105(172)173)15-6-7-29-108;/h2-5,11-14,19-26,39-41,52-53,63,66-81,118-119,142-147,174-175H,6-10,15-18,27-38,42-51,108-109H2,1H3,(H2,110,148)(H,115,124)(H,120,149)(H,121,156)(H,122,157)(H,123,170)(H,125,161)(H,126,152)(H,127,151)(H,128,150)(H,129,163)(H,130,166)(H,131,160)(H,132,167)(H,133,168)(H,134,169)(H,135,162)(H,136,159)(H,137,155)(H,138,158)(H,139,164)(H,140,165)(H,153,154)(H,172,173)(H4,111,112,116)(H4,113,114,117);1H/t53-,63-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-;/m0./s1 |
| Inchi Key | DTVJLSGONKKSLF-ZJWGRDAKSA-N |
| SMILES | O=C(NCC(N[C@@H](CCC(N)=O)C(N[C@@H](CC1=CC=C(O)C=C1)C(N[C@H](C(N[C@@H](CO)C(N[C@@H](CC2=CC=C(O)C=C2)C(N[C@@H](CC3=CNC=N3)C(N[C@@H](CS[H])C(N[C@@H](CC4=CNC5=C4C=CC=C5)C(N[C@@H](CS[H])C(N[C@@H](CC6=CNC7=C6C=CC=C7)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(O)=O)C(N8CCC[C@H]8C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CO)C(NCC(NCC(N[C@@H](CO)C(N[C@@H](CCCCN[H])C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C)=O)=O)=O)[C@H](CO)N[H].Cl |
| Size | 5 mg |
| Supplier Page | https://www.caymanchem.com/product/37410 |