(2R)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine

(2R)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine is an intermediate in the preparation of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist.

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Catalog Number	380499-07-0
Alternative Name(s)	Aprepitant dehydro dealkyl; Desfluro Aprepitant; 2H-1,4-Oxazine, 2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-, (2R)-; (R)-6-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine; 2alpha-[(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine; Aprepitant Impurity 6
Molecular Formula	C20H16F7NO2
CAS#	380499-07-0
Purity	≥95%
Inchi	InChI=1S/C20H16F7NO2/c1-11(13-8-14(19(22,23)24)10-15(9-13)20(25,26)27)30-18-17(28-6-7-29-18)12-2-4-16(21)5-3-12/h2-5,8-11,18H,6-7H2,1H3/t11-,18-/m1/s1
Inchi Key	KHOSCFXAHZBOCH-ADLMAVQZSA-N
Size	Please inquire
Supplier Page	https://www.bocsci.com/product/2r-2-1r-1-3-5-bis-trifluoromethyl-phenyl-ethoxy-cas-380499-07-0-117867.html