ZQ 16
ZQ 16 is a selective medium-chain free fatty acid receptor GPR84 agonist (EC50 = 139 nM), displaying no activity at GPR40, GPR41, GPR119 or GPR120 at 100 μM. ZQ 16 activates GPR84-mediated calcium mobilization, inhibits cAMP accumulation, and induces ERK1/2 phosphorylation, receptor desensitization and internalization in vitro.
Catalog Number | 376616-73-8 |
Alternative Name(s) | ZQ 16; ZQ16; ZQ-16; 2-(Hexylthio)-6-hydroxy-4(3H)-pyrimidinone |
Molecular Formula | C10H16N2O2S |
CAS# | 376616-73-8 |
Purity | ≥98% |
Inchi | InChI=1S/C10H16N2O2S/c1-2-3-4-5-6-15-10-11-8(13)7-9(14)12-10/h7H,2-6H2,1H3,(H2,11,12,13,14) |
Inchi Key | UYXOAKRMLQKLQX-UHFFFAOYSA-N |
Size | Please inquire |
Supplier Page | https://www.bocsci.com/zq-16-cas-376616-73-8-item-170444.html |