β-NF-JQ1

β-NF-JQ1 is a PROTAC that recruits Aryl Hydrocarbon Receptor E3 ligase to target proteins. It uses β-NF as an AhR ligand to act directly on bromodomain-containing (BRD) proteins, induces the interaction between AhR and BRD proteins and exhibits effective anticancer activity related to protein knockdown activity.

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Catalog Number	2380000-55-3
Alternative Name(s)	beta-NF-JQ1; (S)-2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-(2-(2-(2-((4-(1-oxo-1H-benzo[f]chromen-3-yl)benzyl)oxy)ethoxy)ethoxy)ethyl)acetamide; 6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide, 4-(4-chlorophenyl)-2,3,9-trimethyl-N-[2-[2-[2-[[4-(1-oxo-1H-naphtho[2,1-b]pyran-3-yl)phenyl]methoxy]ethoxy]ethoxy]ethyl]-, (6S)-; (6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-N-[2-[2-[2-[[4-(1-oxo-1H-naphtho[2,1-b]pyran-3-yl)phenyl]methoxy]ethoxy]ethoxy]ethyl]-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide
Molecular Formula	C45H42ClN5O6S
CAS#	2380000-55-3
Purity	≥95%
Inchi	InChI=1S/C45H42ClN5O6S/c1-27-28(2)58-45-41(27)43(33-12-15-34(46)16-13-33)48-36(44-50-49-29(3)51(44)45)24-40(53)47-18-19-54-20-21-55-22-23-56-26-30-8-10-32(11-9-30)39-25-37(52)42-35-7-5-4-6-31(35)14-17-38(42)57-39/h4-17,25,36H,18-24,26H2,1-3H3,(H,47,53)/t36-/m0/s1
Inchi Key	OZFKLXDOAZGVSV-BHVANESWSA-N
Size	Please inquire
Supplier Page	https://ptc.bocsci.com/product/nf-jq1-cas-2380000-55-3-380709.html