α-Conotoxin ImI
α-Conotoxin ImI is a nicotinic acetylcholine receptor ligand isolated from the snail Conus imperialis. It shows selectivity for homomeric α7 and α9 receptors with IC50 values of 220 and 1800 nM respectively, but shows no effect on α2β2, α2β4, α3β2, α3β3, α4β2 and α4β4 subunit combinations. It mainly acts as an antagonist in central nervous system. It was sold under license for Cognetix for research purposes only.
| Catalog Number | 156467-85-5 |
| Alternative Name(s) | alpha-Ctx-imi |
| Molecular Formula | C18H19ClN4O.HCl |
| CAS# | 156467-85-5 |
| Inchi | InChI=1S/C52H82N20O15S4/c1-24(41(78)66-30(15-25-18-61-27-8-3-2-7-26(25)27)44(81)64-28(9-4-12-59-51(55)56)42(79)69-33(20-88)40(54)77)62-46(83)35(22-90)70-43(80)29(10-5-13-60-52(57)58)65-49(86)37-11-6-14-72(37)50(87)31(16-39(75)76)67-45(82)32(19-73)68-48(85)36(23-91)71-47(84)34(21-89)63-38(74)17-53/h2-3,7-8,18,24,28-37,61,73,88-91H,4-6,9-17,19-23,53H2,1H3,(H2,54,77)(H,62,83)(H,63,74)(H,64,81)(H,65,86)(H,66,78)(H,67,82)(H,68,85)(H,69,79)(H,70,80)(H,71,84)(H,75,76)(H4,55,56,59)(H4,57,58,60)/t24-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-/m0/s1 |
| Inchi Key | IFMXNBRHEQLZMI-VAYQAVKTSA-N |
| Size | Please inquire |
| Supplier Page | https://www.bocsci.com/conotoxin-imi-cas-156467-85-5-item-235752.html |