(2S)-2-Hydroxyglutaric acid

(2S)-2-Hydroxyglutaric acid, an epigenetic modifier and putative oncometabolite of kidney cancer, inhibits histone demethylase, thereby promoting histone methylation. It inhibits mitochondrial creatine kinase (Mi-CK) activity with Km and Ki of 2.52 mM and 11.13 mM, respectively.

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Catalog Number 13095-48-2
Alternative Name(s) (S)-2-Hydroxyglutaric acid; L-2-Hydroxyglutaric acid; (S)-α-Hydroxyglutaric Acid; L-alpha-Hydroxyglutaric acid; 2-hydroxy-L-Glutaric acid; 2-hydroxy-(S)-Pentanedioic acid; L-2-Hydroxyglutarate
Molecular Formula C5H8O5
CAS# 13095-48-2
Purity ≥95%
Inchi InChI=1S/C5H8O5/c6-3(5(9)10)1-2-4(7)8/h3,6H,1-2H2,(H,7,8)(H,9,10)/t3-/m0/s1
Inchi Key HWXBTNAVRSUOJR-VKHMYHEASA-N
Size Please inquire
Supplier Page https://www.bocsci.com/2s-2-hydroxyglutaric-acid-cas-13095-48-2-item-163524.html