ZLJ-6 is a dual inhibitor of COX and 5-lipoxygenase (5-LO) with IC50 values of 0.73, 0.31, and 0.99 μM for COX-1, COX-2, and 5-LO, respectively. It reduces carrageenin-induced paw edema (inflammation) in rats and acetic acid-induced abdominal constriction (pain) in mice without causing gastrointestinal ulcers, a common side effect of non-selective COX inhibitors.