N-p-Tosyl-Gly-Pro-Lys p-nitroanilide acetate salt

N-p-Tosyl-Gly-Pro-Lys-pNA is a colorimetric substrate for plasmin. Plasmin binds and hydrolyzes N-p-tosyl-Gly-Pro-Lys-pNA to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of plasmin activity.

Catalog Number R1907
Alternative Name(s) N-(p-Tosyl)-Gly-Pro-Lys 4-nitroanilide acetate salt, Tos-GPK-pNA, Tos-Gly-Pro-Lys-pNA acetate
Molecular Formula C26H34N6O7S • C2H4O2
CAS# 88793-79-7
Purity >95%
Inchi InChI=1S/C26H34N6O7S.C2H4O2/c1-18-7-13-21(14-8-18)40(38,39)28-17-24(33)31-16-4-6-23(31)26(35)30-22(5-2-3-15-27)25(34)29-19-9-11-20(12-10-19)32(36)37;1-2(3)4/h7-14,22-23,28H,2-6,15-17,27H2,1H3,(H,29,34)(H,30,35);1H3,(H,3,4)/t22-,23-;/m0./s1
Inchi Key KPGSNEYSJPIZCW-SJEIDVEUSA-N
SMILES CC1=CC=C(C=C1)S(=O)(=O)NCC(=O)N2CCC[C@H]2C(=O)N[C@@H](CCCCN)C(=O)NC3=CC=C(C=C3)[N+](=O)[O-].CC(=O)O
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