Z-YVAD-FMK

Irreversible, cell permeable caspase-1 (ICE) inhibitor. Inhibits also caspase-4.

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Catalog Number HB00045
Alternative Name(s) Caspase-1 Inhibitor, Z-YVAD fluoromethylketone
Research Area Cell permeable fluoromethyl ketone (FMK)-derivatized peptides act as effective irreversible Caspase inhibitors with no cytotoxic effects and, therefore, are useful tools for studying Caspase activity.
Molecular Formula C31H39FN4O9
Purity >98%
Inchi InChI=1S/C31H39FN4O9/c1-18(2)27(30(42)33-19(3)28(40)34-23(25(38)16-32)15-26(39)44-4)36-29(41)24(14-20-10-12-22(37)13-11-20)35-31(43)45-17-21-8-6-5-7-9-21/h5-13,18-19,23-24,27,37H,14-17H2,1-4H3,(H,33,42)(H,34,40)(H,35,43)(H,36,41)/t19-,23-,24?,27-/m0/s1
Inchi Key MVPQJUFFTWWKBT-UYDLRUHXSA-N
SMILES C[C@@H](C(=O)N[C@@H](CC(=O)OC)C(=O)CF)NC(=O)[C@H](C(C)C)NC(=O)C(CC1=CC=C(C=C1)O)NC(=O)OCC2=CC=CC=C2
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Supplier Page https://www.creative-peptides.com/product/z-yvad-fmk-item-hb00045-917.html