MLi-2

MLi-2 is an orally active and highly selective inhibitor of LRRK2. MLi-2 exhibits exceptional potency in a purified LRRK2 kinase assay in vitro with IC50 of 0.76 nM, a cellular assay monitoring dephosphorylation of LRRK2 pSer935 LRRK2 with IC50 of 1.4 nM, and a radioligand competition binding assay with IC50 of 3.4 nM.

Price Not Available 10mM/1mL MLi-2 Supplier Page

Trivial name	N/A
Catalog Number	S9694
Molecular Formula	C21H25N5O2
CAS#	1627091-47-7
SMILES	CC1CN(CC(C)O1)C2=CC(=NC=N2)C3=N[NH]C4=CC=C(OC5(C)CC5)C=C34
Size	10mM/1mL
Supplier Page	http://www.selleckchem.com/products/mli-2.html
Additional Information	https://file.selleck.cn/downloads/struct/s9694-mli-2-chemical-structure.gif