ML385
ML385 is a novel and specific NRF2 inhibitor with an IC50 of 1.9 μM. It inhibits the downstream target gene expression of NRF2. NRF2 regulates the activity of several ferroptosis and lipid peroxidation-related proteins.
| Trivial name | N/A |
| Catalog Number | S8790 |
| Molecular Formula | C29H25N3O4S |
| CAS# | 846557-71-9 |
| Inchi | InChI=1S/C29H25N3O4S/c1-17-5-3-4-6-22(17)28(34)32-12-11-20-15-21(8-9-23(20)32)27-18(2)37-29(31-27)30-26(33)14-19-7-10-24-25(13-19)36-16-35-24/h3-10,13,15H,11-12,14,16H2,1-2H3,(H,30,31,33) |
| Inchi Key | LINHYWKZVCNAMQ-UHFFFAOYSA-N |
| SMILES | CC1=CC=CC=C1C(=O)N2CCC3=C2C=CC(=C3)C4=C(SC(=N4)NC(=O)CC5=CC6=C(C=C5)OCO6)C |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/ml385.html |
| Additional Information | https://file.selleck.cn/downloads/struct/ml385-chemical-structure-s8790.gif |