Ulixertinib (BVD-523)
Ulixertinib (BVD-523, VRT752271) is a potent and reversible ERK1/ERK2 inhibitor with IC50 of <0.3 nM for ERK2. Phase 1.
| Trivial name | VRT752271 |
| Catalog Number | S7854 |
| Molecular Formula | C21H22Cl2N4O2 |
| CAS# | 869886-67-9 |
| Inchi | InChI=1S/C21H22Cl2N4O2/c1-12(2)26-20-8-16(17(23)10-25-20)14-7-18(24-9-14)21(29)27-19(11-28)13-4-3-5-15(22)6-13/h3-10,12,19,24,28H,11H2,1-2H3,(H,25,26)(H,27,29)/t19-/m1/s1 |
| Inchi Key | KSERXGMCDHOLSS-LJQANCHMSA-N |
| SMILES | CC(C)NC1=NC=C(C(=C1)C2=CNC(=C2)C(=O)NC(CO)C3=CC(=CC=C3)Cl)Cl |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/ulixertinib-bvd-523-vrt752271.html |
| Additional Information | https://file.selleck.cn/downloads/struct/bvd-523-chemical-structure-s7854.gif |