Ribociclib
Ribociclib is an orally available, and highly specific inhibitor of CDK4 and CDK6 with IC50 of 10 nM and 39 nM. Phase 3.
| Trivial name | LEE011 |
| Catalog Number | S7440 |
| Molecular Formula | C23H30N8O |
| CAS# | 1211441-98-3 |
| Inchi | InChI=1S/C23H30N8O/c1-29(2)22(32)19-13-16-14-26-23(28-21(16)31(19)17-5-3-4-6-17)27-20-8-7-18(15-25-20)30-11-9-24-10-12-30/h7-8,13-15,17,24H,3-6,9-12H2,1-2H3,(H,25,26,27,28) |
| Inchi Key | RHXHGRAEPCAFML-UHFFFAOYSA-N |
| SMILES | CN(C)C(=O)C1=CC2=CN=C(N=C2N1C3CCCC3)NC4=NC=C(C=C4)N5CCNCC5 |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/lee011.html |
| Additional Information | https://file.selleck.cn/downloads/struct/LEE011-2-chemical-structure-s7440.gif |