Aloxistatin (E64d)

Aloxistatin (E64d) is an irreversible and membrane-permeable cysteine protease inhibitor with blood platelet aggregation inhibiting activity. The cysteine protease cathepsin L is required for SARS-CoV-2 viral entry, and aloxistatin treatment reduced cellular entry of SARS-CoV-2 pseudovirions by 92.3%.

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Trivial name	E-64d
Catalog Number	S7393
Molecular Formula	C17H30N2O5
CAS#	88321-09-9
Inchi	InChI=1S/C17H30N2O5/c1-6-23-17(22)14-13(24-14)16(21)19-12(9-11(4)5)15(20)18-8-7-10(2)3/h10-14H,6-9H2,1-5H3,(H,18,20)(H,19,21)/t12-,13-,14-/m0/s1
Inchi Key	SRVFFFJZQVENJC-IHRRRGAJSA-N
SMILES	CCOC(=O)C1C(O1)C(=O)NC(CC(C)C)C(=O)NCCC(C)C
Size	10mM/1mL
Supplier Page	http://www.selleckchem.com/products/Aloxistatin.html
Additional Information	https://file.selleck.cn/downloads/struct/E-64d-Aloxistatin-Loxistatin-chemical-structure-s7393.gif