RepSox (E-616452)
RepSox (E-616452, SJN 2511, ALK5 Inhibitor II) is a potent and selective inhibitor of the TGFβR-1/ALK5 with IC50 of 23 nM and 4 nM for ATP binding to ALK5 and ALK5 autophosphorylation in cell-free assays, respectively.
| Trivial name | SJN 2511,ALK5 Inhibitor II |
| Catalog Number | S7223 |
| Molecular Formula | C17H13N5 |
| CAS# | 446859-33-2 |
| Inchi | InChI=1S/C17H13N5/c1-11-4-2-5-16(20-11)17-12(10-19-22-17)13-7-8-14-15(21-13)6-3-9-18-14/h2-10H,1H3,(H,19,22) |
| Inchi Key | LBPKYPYHDKKRFS-UHFFFAOYSA-N |
| SMILES | CC1=NC(=CC=C1)C2=C(C=NN2)C3=NC4=C(C=C3)N=CC=C4 |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/repsox.html |
| Additional Information | https://file.selleck.cn/downloads/struct/RepSox-chemical-structure-s7223.gif |