Talazoparib (BMN 673)

Talazoparib (BMN 673, LT-673) is a novel PARP inhibitor with IC50 of 0.57 nM for PARP1 in a cell-free assay. It is also a potent inhibitor of PARP-2, but does not inhibit PARG and is highly sensitive to PTEN mutation. Phase 3.

Price Not Available 10mM/1mL Talazoparib (BMN 673) Supplier Page

Trivial name	LT-673
Catalog Number	S7048
Molecular Formula	C19H14F2N6O
CAS#	1207456-01-6
Inchi	InChI=1S/C19H14F2N6O/c1-27-18(22-8-23-27)15-16(9-2-4-10(20)5-3-9)24-13-7-11(21)6-12-14(13)17(15)25-26-19(12)28/h2-8,15-16,24H,1H3,(H,26,28)/t15-,16-/m1/s1
Inchi Key	HWGQMRYQVZSGDQ-HZPDHXFCSA-N
SMILES	CN1C(=NC=N1)C2C(NC3=CC(=CC4=C3C2=NNC4=O)F)C5=CC=C(C=C5)F
Size	10mM/1mL
Supplier Page	http://www.selleckchem.com/products/bmn-673.html
Additional Information	https://file.selleck.cn/downloads/struct/BMN-673-chemical-structure-s7048.gif