Gap19
Gap19 is a nonapeptide derived from the cytoplasmic loop (CL) of Cx43 and acts as a selective connexin 43 (Cx43) hemichannel blocker. Gap19 blocks Cx43 hemichannels without inhibiting gap junctions (GJs) at IC50 of 6.5 μM when applied intracellulary.
| Trivial name | N/A |
| Catalog Number | S6946 |
| Molecular Formula | C55H96N14O13 |
| CAS# | 1507930-57-5 |
| SMILES | CCC(C)C(NC(=O)C(CCC(O)=O)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(N)CCCCN)C(C)CC)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CCCCN)C(O)=O |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/gap19.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s6946-gap19-chemical-structure.gif |