UCB-9260
UCB-9260 is an orally active inhibitor that inhibits TNF signalling by stabilising an asymmetric form of the trimer. UCB-9260 binds TNF with Kd of 13 nM. UCB-9260 also inhibits NF-κB with IC50 of 202 nM after TNF stimulation.
Trivial name | N/A |
Catalog Number | S3231 |
Molecular Formula | C26H25N5O |
CAS# | 1515888-53-5 |
SMILES | C[N]1C=C(C=N1)C2=CC3=C(C=C2)N=C(C(O)C4=CC=NC=C4)[N]3CC5=C(C)C=CC(=C5)C |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/ucb-9260.html |
Additional Information | https://file.selleck.cn/downloads/struct/s3231-ucb-9260-chemical-structure.gif |