L-2-Hydroxyglutaric acid disodium
L-2-Hydroxyglutaric acid disodium ((S)-2-Hydroxyglutaric acid disodium, L-2-Hydroxyglutarate disodium, LGA, L-2HG) is an epigenetic modifier and a putative oncometabolite in kidney cancer that inhibits histone demethylases and hence promotes histone methylation. L-2-Hydroxyglutaric acid disodium is also an inhibitor of mitochondrial creatine kinase (Mi-CK) with Km and Ki of 2.52 mM and 11.13 mM, respectively.
| Trivial name | (S)-2-Hydroxyglutaric acid disodium, L-2-Hydroxyglutarate disodium, LGA, L-2HG |
| Catalog Number | S1325 |
| Molecular Formula | C5H6Na2O5 |
| CAS# | 63512-50-5 |
| SMILES | [Na+].[Na+].OC(CCC([O-])=O)C([O-])=O |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/l-2-hydroxyglutaric-acid-disodium.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s1325-l-2-hydroxyglutaric-acid-disodium-chemical-structure.gif |