SAR156497 10mg

SAR156497 is an exquisitely selective Aurora A, B, and C inhibitor with in vitro and in vivo efficacy with IC50 = 0.5 nM (Aurora A), 1 nM (Aurora B / incenp), 3 nM (Aurora C / incenp) respectively SAR156497 combines high in vitro potency with satisfactory metabolic stability and limited CYP 3A4 and PDE3 inhibition.

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Trivial name	SAR156497 10mg
Catalog Number	A14382-10
Alternative Name(s)	(S)-ethyl 9-(3-((1H-benzo[d]imidazol-2-yl)oxy)phenyl)-8-oxo-4,5,6,7,8,9-hexahydro-2H-pyrrolo[3,4-b]quinoline-3-carboxylate
Molecular Formula	C27H24N4O4
CAS#	1256137-14-0
SMILES	O=C(C1=C2NC3=C(C(CCC3)=O)[C@@H](C4=CC=CC(OC5=NC6=CC=CC=C6N5)=C4)C2=CN1)OCC
Size	10mg
Supplier Page	http://www.adooq.com/sar156497.html