IWP-3 10mg

IWP-3 is an inhibitor of Wnt production. Blocks Wnt pathway activity in vitro ( IC?????€ = 40 nM). IWP-3 inactivates Porcupine (Porcn), a membrane-bound O-acyltransferase responsible for palmitoylating Wnt proteins, which is essential for their signaling ability and secretion. Through blockade of Wnt signaling, IWP-3 has been used to promote cardiomyocyte generation from human embryonic stem cells (EC?????€ = 1.2 ??M).

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Trivial name	IWP-3 10mg
Catalog Number	A13192-10
Alternative Name(s)	2-?[[3-?(4-?fluorophenyl)-?3,?4,?6,?7-?tetrahydro-?4-?oxothieno[3,?2-? d]pyrimidin-?2-?yl]thio]-?N-?(6-?methyl-?2-?benzothiazolyl)-?acetamide
Molecular Formula	C22H17FN4O2S3
CAS#	687561-60-0
SMILES	O=C(CSC(N1C2=CC=C(F)?C=C2)?=NC3=C(SCC3)?C1=O)?NC4=NC5=C(C=C(C)?C=C5)?S4
Size	10mg
Supplier Page	http://www.adooq.com/iwp-3.html