GSK-J4 10mg

GSK J4 is a cell permeable prodrug rapidly hydrolyzed by macrophage esterases to GSK-J1, a potent selective jumonji H3K27 demethylase inhibitor; attenuates lipopolysaccharide (LPS)-induced proinflammatory cytokine production in primary human macrophages (IC50 = 9 uM for the inhibition of TNF?? release).

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Trivial name	GSK-J4 10mg
Catalog Number	A12732-10
Alternative Name(s)	ethyl 3-[[2-pyridin-2-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoate
Molecular Formula	C24H27N5O2
CAS#	1373423-53-0
SMILES	N/A
Size	10mg
Supplier Page	http://www.adooq.com/gsk-j4.html