AZ 3146 50mg
AZ 3146 is a potent and selective monopolar spindle 1 (Mps1) kinase inhibitor (IC50 = 35 nM). It interferes with chromosome alignment and overrides spindle assembly checkpoint and also Inhibits the recruitment of Mad1, Mad2 and centromere protein E (CENP-E) to kinetochores.
Trivial name | AZ 3146 50mg |
Catalog Number | A11170-50 |
Alternative Name(s) | 9-Cyclopentyl-2-[[2-methoxy-4-[(1-m ethylpiperidin-4-yl)oxy]-phenyl]amino]-7-methyl-7, 9-dihydro-8H-purin-8-one |
Molecular Formula | C24H32N6O3 |
CAS# | 1124329-14-1 |
SMILES | CN1CCC(CC1)OC2=CC(=C(C=C2)NC3=NC=C4C(=N3)N(C(=O)N4C)C5CCCC5)OC |
Size | 50mg |
Supplier Page | http://www.adooq.com/az-3146.html |