KU-0060648
KU-0060648 is a dual inhibitor of DNA-PK and PI3Kα, PI3Kβ, PI3Kδ with IC50 of 8.6 nM and 4 nM, 0.5 nM, 0.1 nM respectively, less inhibition of PI3Kγ with IC50 of 0.59 μM.
| Trivial name | N/A |
| Catalog Number | S8045 |
| Molecular Formula | C33H34N4O4S |
| CAS# | 881375-00-4 |
| Inchi | InChI=1S/C33H34N4O4S/c1-2-35-12-14-36(15-13-35)21-29(39)34-26-11-10-23(33-31(26)25-6-3-4-9-28(25)42-33)22-7-5-8-24-27(38)20-30(41-32(22)24)37-16-18-40-19-17-37/h3-11,20H,2,12-19,21H2,1H3,(H,34,39) |
| Inchi Key | AATCBLYHOUOCTO-UHFFFAOYSA-N |
| SMILES | CCN1CCN(CC1)CC(=O)NC2=C3C4=CC=CC=C4SC3=C(C=C2)C5=CC=CC6=C5OC(=CC6=O)N7CCOCC7 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/ku-0060648.html |
| Additional Information | https://file.selleck.cn/downloads/struct/KUOO60648-chemical-structure-s8045.gif |