Capivasertib (AZD5363)

Capivasertib (AZD5363) potently inhibits all isoforms of Akt(Akt1/Akt2/Akt3) with IC50 of 3 nM/8 nM/8 nM in cell-free assays, similar to P70S6K/PKA and lower activity towards ROCK1/2. Phase 2.

Price Not Available 25mg Capivasertib (AZD5363) Supplier Page
Trivial name N/A
Catalog Number S8019
Molecular Formula C21H25ClN6O2
CAS# 1143532-39-1
Inchi InChI=1S/C21H25ClN6O2/c22-15-3-1-14(2-4-15)17(6-12-29)27-20(30)21(23)7-10-28(11-8-21)19-16-5-9-24-18(16)25-13-26-19/h1-5,9,13,17,29H,6-8,10-12,23H2,(H,27,30)(H,24,25,26)/t17-/m0/s1
Inchi Key JDUBGYFRJFOXQC-KRWDZBQOSA-N
SMILES C1CN(CCC1(C(=O)NC(CCO)C2=CC=C(C=C2)Cl)N)C3=NC=NC4=C3C=CN4
Size 25mg
Supplier Page http://www.selleckchem.com/products/azd5363.html
Additional Information https://file.selleck.cn/downloads/struct/AZD5363-chemical-structure-s8019.gif