Sunitinib
Sunitinib is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRβ with IC50 of 80 nM and 2 nM, and also inhibits c-Kit. Sunitinib is also a dose-dependent inhibitor of the autophosphorylation activity of IRE1α. Sunitinib induces autophagy and apoptosis.
| Trivial name | SU11248 |
| Catalog Number | S7781 |
| CAS# | 557795-19-4 |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/sunitinib.html |
| Additional Information | https://file.selleck.cn/downloads/struct/sunitinib-free-base-chemical-structure-s7781.gif |