Sotuletinib (BLZ945)
Sotuletinib (BLZ945) is an orally active, potent and selective CSF-1R inhibitor with IC50 of 1 nM, >1000-fold selective against its closest receptor tyrosine kinase homologs.
Catalog Number | S7725 |
Molecular Formula | C20H22N4O3S |
CAS# | 953769-46-5 |
Inchi | InChI=1S/C20H22N4O3S/c1-21-19(26)16-10-13(8-9-22-16)27-12-6-7-15-18(11-12)28-20(24-15)23-14-4-2-3-5-17(14)25/h6-11,14,17,25H,2-5H2,1H3,(H,21,26)(H,23,24)/t14-,17-/m1/s1 |
Inchi Key | ADZBMFGQQWPHMJ-RHSMWYFYSA-N |
SMILES | CNC(=O)C1=NC=CC(=C1)OC2=CC3=C(C=C2)N=C(S3)NC4CCCCC4O |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/blz945.html |
Additional Information | https://file.selleck.cn/downloads/struct/blz945-chemical-structure-s7725.gif |