EI1
EI1 is a potent and selective EZH2 inhibitor with IC50 of 15 nM and 13 nM for EZH2 (WT) and EZH2 (Y641F), respectively.
| Trivial name | KB-145943 |
| Catalog Number | S7611 |
| Molecular Formula | C23H26N4O2 |
| CAS# | 1418308-27-6 |
| Inchi | InChI=1S/C23H26N4O2/c1-5-17(6-2)27-8-7-18-19(10-16(12-24)11-21(18)27)22(28)25-13-20-14(3)9-15(4)26-23(20)29/h7-11,17H,5-6,13H2,1-4H3,(H,25,28)(H,26,29) |
| Inchi Key | PFHDWRIVDDIFRP-UHFFFAOYSA-N |
| SMILES | CCC(CC)N1C=CC2=C(C=C(C=C21)C#N)C(=O)NCC3=C(C=C(NC3=O)C)C |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/ei1.html |
| Additional Information | https://file.selleck.cn/downloads/struct/ei1-chemical-structure-s7611.gif |