AT13148
AT13148 is an oral, ATP-competitive, multi-AGC kinase inhibitor with IC50 of 38 nM/402 nM/50 nM, 8 nM, 3 nM, and 6 nM/4 nM for Akt1/2/3, p70S6K, PKA, and ROCKI/II, respectively. Phase 1.
Trivial name | N/A |
Catalog Number | S7563 |
Molecular Formula | C17H16ClN3O |
CAS# | 1056901-62-2 |
Inchi | InChI=1S/C17H16ClN3O/c18-16-7-5-15(6-8-16)17(22,11-19)14-3-1-12(2-4-14)13-9-20-21-10-13/h1-10,22H,11,19H2,(H,20,21)/t17-/m0/s1 |
Inchi Key | IIRWNGPLJQXWFJ-KRWDZBQOSA-N |
SMILES | C1=CC(=CC=C1C2=CNN=C2)C(CN)(C3=CC=C(C=C3)Cl)O |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/at13148.html |
Additional Information | https://file.selleck.cn/downloads/struct/at13148-chemical-structure-s7563.gif |