G-749
G-749 is a novel and potent FLT3 inhibitor with IC50 of 0.4 nM, 0.6 nM and 1 nM for FLT3 (WT), FLT3 (D835Y), and Mer, respectively, showing lower potency against other tyrosine kinases.
| Trivial name | N/A |
| Catalog Number | S7545 |
| Molecular Formula | C25H25BrN6O2 |
| CAS# | 1457983-28-6 |
| Inchi | InChI=1S/C25H25BrN6O2/c1-32-13-11-17(12-14-32)29-25-30-22-20(26)15-27-24(33)21(22)23(31-25)28-16-7-9-19(10-8-16)34-18-5-3-2-4-6-18/h2-10,15,17H,11-14H2,1H3,(H,27,33)(H2,28,29,30,31) |
| Inchi Key | SXWMIXPJPNCXQQ-UHFFFAOYSA-N |
| SMILES | CN1CCC(CC1)NC2=NC3=C(C(=O)NC=C3Br)C(=N2)NC4=CC=C(C=C4)OC5=CC=CC=C5 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/g-749.html |
| Additional Information | https://file.selleck.cn/downloads/struct/g-749-chemical-structure-s7545.gif |