FTI 277 HCl

FTI 277 HCl is a potent and selective farnesyltransferase (FTase) inhibitor with IC50 of 500 pM, about 100-fold selectivity over the closely related GGTase I. FTI 277 HCl inhibits cell growth and induces apoptosis. FTI 277 HCl is effective in clearing HDV viremia.

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Trivial name	N/A
Catalog Number	S7465
Molecular Formula	C22H30ClN3O3S2
CAS#	180977-34-8
Inchi	InChI=1S/C22H29N3O3S2.ClH/c1-28-22(27)20(10-11-30-2)25-21(26)18-9-8-17(24-13-16(23)14-29)12-19(18)15-6-4-3-5-7-15;/h3-9,12,16,20,24,29H,10-11,13-14,23H2,1-2H3,(H,25,26);1H/t16-,20+;/m1./s1
Inchi Key	PIAFFJUUNXEDEW-PXPMWPIZSA-N
SMILES	COC(=O)C(CCSC)NC(=O)C1=C(C=C(C=C1)NCC(CS)N)C2=CC=CC=C2.Cl
Size	100mg
Supplier Page	http://www.selleckchem.com/products/fti-277-hcl.html
Additional Information	https://file.selleck.cn/downloads/struct/fti-277-hcl-chemical-structure-s7465.gif