PFI-2 HCl
PFI-2 is a potent, selective, and cell-active lysine methyltransferase SETD7 inhibitor with Ki (app) and IC50 of 0.33 nM and 2 nM, 1000-fold selectivity over other methyltransferases and other non-epigenetic targets.
| Trivial name | N/A |
| Catalog Number | S7294 |
| Molecular Formula | C23H25F4N3O3S.HCl |
| CAS# | 1627607-87-7 |
| Inchi | InChI=1S/C23H25F4N3O3S/c24-20-13-18(12-16-6-7-28-14-19(16)20)34(32,33)29-21(22(31)30-8-1-2-9-30)11-15-4-3-5-17(10-15)23(25,26)27/h3-5,10,12-13,21,28-29H,1-2,6-9,11,14H2/t21-/m1/s1 |
| Inchi Key | JCKGSPAAPQRPBW-OAQYLSRUSA-N |
| SMILES | C1CCN(C1)C(=O)C(CC2=CC(=CC=C2)C(F)(F)F)NS(=O)(=O)C3=CC4=C(CNCC4)C(=C3)F.Cl |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/pfi-2.html |
| Additional Information | https://file.selleck.cn/downloads/struct/pfi-2-chemical-structure-s7294.gif |