AGI-5198
AGI-5198 (IDH-C35) is the first highly potent and selective inhibitor of IDH1 R132H/R132C mutants with IC50 of 0.07 μM/0.16 μM.
| Trivial name | IDH-C35 |
| Catalog Number | S7185 |
| Molecular Formula | C27H31FN4O2 |
| CAS# | 1355326-35-0 |
| Inchi | InChI=1S/C27H31FN4O2/c1-19-9-6-7-14-24(19)26(27(34)30-22-11-4-3-5-12-22)32(23-13-8-10-21(28)17-23)25(33)18-31-16-15-29-20(31)2/h6-10,13-17,22,26H,3-5,11-12,18H2,1-2H3,(H,30,34) |
| Inchi Key | FNYGWXSATBUBER-UHFFFAOYSA-N |
| SMILES | CC1=CC=CC=C1C(C(=O)NC2CCCCC2)N(C3=CC(=CC=C3)F)C(=O)CN4C=CN=C4C |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/agi-5198.html |
| Additional Information | https://file.selleck.cn/downloads/struct/AGI5198-chemical-structure-s7185.gif |