AZD3463
AZD3463 is a novel orally bioavailable ALK inhibitor with Ki of 0.75 nM, which also inhibits IGF1R with equivalent potency. AZD3463 suppresses cell viability by inducing both cell apoptosis and autophagy.
| Trivial name | N/A |
| Catalog Number | S7106 |
| Molecular Formula | C24H25ClN6O |
| CAS# | 1356962-20-3 |
| Inchi | InChI=1S/C24H25ClN6O/c1-32-22-12-16(31-10-8-15(26)9-11-31)6-7-21(22)29-24-28-14-19(25)23(30-24)18-13-27-20-5-3-2-4-17(18)20/h2-7,12-15,27H,8-11,26H2,1H3,(H,28,29,30) |
| Inchi Key | GCYIGMXOIWJGBU-UHFFFAOYSA-N |
| SMILES | COC1=C(C=CC(=C1)N2CCC(CC2)N)NC3=NC=C(C(=N3)C4=CNC5=CC=CC=C54)Cl |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/azd3463.html |
| Additional Information | https://file.selleck.cn/downloads/struct/AZD3463-chemical-structure-s7106.gif |