MK-8745
MK-8745 is a potent and selective Aurora A inhibitor with IC50 of 0.6 nM, more than 450-fold selectivity for Aurora A over Aurora B.
| Trivial name | N/A |
| Catalog Number | S7065 |
| Molecular Formula | C20 H19 Cl F N5 O S |
| CAS# | 885325-71-3 |
| Inchi | InChI=1S/C20H19ClFN5OS/c21-16-5-2-4-15(18(16)22)19(28)27-10-8-26(9-11-27)13-14-3-1-6-17(24-14)25-20-23-7-12-29-20/h1-7,12H,8-11,13H2,(H,23,24,25) |
| Inchi Key | YCRFPWKUUNKNDN-UHFFFAOYSA-N |
| SMILES | C1CN(CCN1CC2=NC(=CC=C2)NC3=NC=CS3)C(=O)C4=C(C(=CC=C4)Cl)F |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/mk-8745.html |
| Additional Information | https://file.selleck.cn/downloads/struct/MK8745-chemical-structure-s7065.gif |