Pinometostat (EPZ5676)
Pinometostat (EPZ5676) is an S-adenosyl methionine (SAM) competitive inhibitor of protein methyltransferase DOT1L with Ki of 80 pM in a cell-free assay, demonstrating >37,000-fold selectivity against all other PMTs tested, inhibits H3K79 methylation in tumor. Phase 1.
| Trivial name | N/A |
| Catalog Number | S7062 |
| CAS# | 1380288-87-8 |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/epz-5676.html |
| Additional Information | https://file.selleck.cn/downloads/struct/EPZ-5676-chemical-structure-s7062.gif |