Brefeldin A (BFA)
Brefeldin A (BFA) is a lactone antibiotic and ATPase inhibitor for protein transport with IC50 of 0.2 μM in HCT 116 cells, induces cancer cell differentiation and apoptosis. It could also improve the HDR(homology-directed repair) efficiency and be an enhancer of CRISPR-mediated HDR. Brefeldin A is also an inhibitor of autophagy and mitophagy.
| Trivial name | Cyanein, Decumbin |
| Catalog Number | S7046 |
| CAS# | 20350-15-6 |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/brefeldin-a.html |
| Additional Information | https://file.selleck.cn/downloads/struct/brefeldin-A-chemical-structure-s7046.gif |