SN-38
SN-38 (NK012) is an active metabolite of CPT-11, inhibits DNA topoisomerase I, DNA synthesis and causes frequent DNA single-strand breaks. SN-38 induces autophagy.
| Trivial name | NK012 |
| Catalog Number | S4908 |
| Molecular Formula | C18H16Cl2N4O2 |
| CAS# | 86639-52-3 |
| Inchi | InChI=1S/C18H16Cl2N4O2/c19-12-5-10(9-1-2-14(21)22-6-9)16-11-7-24(15(26)8-25)4-3-13(11)23-18(16)17(12)20/h1-2,5-6,23,25H,3-4,7-8H2,(H2,21,22) |
| Inchi Key | VVUOUIPXYFIWLE-UHFFFAOYSA-N |
| SMILES | C1CN(CC2=C1NC3=C2C(=CC(=C3Cl)Cl)C4=CN=C(C=C4)N)C(=O)CO |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/sn-38.html |
| Additional Information | https://file.selleck.cn/downloads/struct/SN-38-chemical-structure-s4908.gif |