QNZ (EVP4593)
QNZ (EVP4593) shows potent inhibitory activity toward both NF-κB activation and TNF-α production with IC50 of 11 nM and 7 nM in Jurkat T cells, respectively.
| Trivial name | N/A |
| Catalog Number | S4902 |
| Molecular Formula | C20H19N3O4 |
| CAS# | 545380-34-5 |
| Inchi | InChI=1S/C20H19N3O4/c1-23-9-8-20(26,19(23)25)7-6-13-4-3-5-14(10-13)16-11-15(27-2)12-17(22-16)18(21)24/h3-5,10-12,26H,8-9H2,1-2H3,(H2,21,24)/t20-/m0/s1 |
| Inchi Key | LQSHXYHWYGKAMX-FQEVSTJZSA-N |
| SMILES | CN1CCC(C1=O)(C#CC2=CC(=CC=C2)C3=NC(=CC(=C3)OC)C(=O)N)O |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/qnz-evp4593.html |
| Additional Information | https://file.selleck.cn/downloads/struct/QNZ-chemical-structure-s4902.gif |