Diminazene Aceturate
Diminazene(Diminazene diaceturate) is a di-amidine also known as 4,4-(1-Triazene–1,3–diyl)bis(benzenecarboximidamide), used as an effective trypanocidal agent. The main biochemical mechanism of the trypanocidal actions of Diminazene aceturate is by binding to trypanosomal kinetoplast DNA (kDNA) in a non-intercalative manner through specific interaction with sites rich in adenine-thymine base pairs. Diminazene aceturate is also an angiotensin-converting enzyme 2 (ACE2) activator and has strong and potent anti-inflammatory properties.
Trivial name | Diminazene diaceturate |
Catalog Number | S4104 |
Molecular Formula | C19H17N5O3 |
CAS# | 908-54-3 |
Inchi | InChI=1S/C19H17N5O3/c20-19-22-14-9-12(1-3-16(14)27-19)13-2-4-17-21-10-15(24(17)11-13)18(25)23-5-7-26-8-6-23/h1-4,9-11H,5-8H2,(H2,20,22) |
Inchi Key | BLGWHBSBBJNKJO-UHFFFAOYSA-N |
SMILES | C1COCCN1C(=O)C2=CN=C3N2C=C(C=C3)C4=CC5=C(C=C4)OC(=N5)N |
Size | 50mg |
Supplier Page | http://www.selleckchem.com/products/diminazene-aceturate.html |
Additional Information | https://file.selleck.cn/downloads/struct/diminazene-aceturate-chemical-structure-S4104.gif |