Miltefosine
Miltefosine (Hexadecylphosphocholine) inhibits PI3K/Akt activity with ED50 of 17.2 μM and 8.1 μM in carcinoma cell lines A431 and HeLa, first oral drug for Visceral leishmaniasis, effective against both promastigotes and amastigotes.
| Trivial name | Hexadecylphosphocholine |
| Catalog Number | S3056 |
| Molecular Formula | C28H32ClN7O |
| CAS# | 58066-85-6 |
| Inchi | InChI=1S/C28H32ClN7O/c1-4-36-26-21(16-32-28(34-26)31-10-7-19-8-11-35(3)12-9-19)13-23(27(36)37)22-6-5-20(14-24(22)29)25-17-30-15-18(2)33-25/h5-6,13-17,19H,4,7-12H2,1-3H3,(H,31,32,34) |
| Inchi Key | RYCBSFIKWACFBY-UHFFFAOYSA-N |
| SMILES | CCN1C2=NC(=NC=C2C=C(C1=O)C3=C(C=C(C=C3)C4=NC(=CN=C4)C)Cl)NCCC5CCN(CC5)C |
| Size | 500mg |
| Supplier Page | http://www.selleckchem.com/products/miltefosine-hexadecylphosphocholine.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Miltefosine-chemical-structure-s3056.gif |