Rivaroxaban
Rivaroxaban is a direct inhibitor of Factor Xa with Ki and IC50 of 0.4 nM and 0.7 nM in cell-free assays, respectively. It is selective for human factor Xa, for which it has >10 000-fold greater selectivity than for other biologically relevant serine proteases (IC50 >20 μM).
| Trivial name | BAY 59-7939 |
| Catalog Number | S3002 |
| Molecular Formula | C19H18ClN3O5S |
| CAS# | 366789-02-8 |
| Inchi | InChI=1S/C19H18ClN3O5S/c20-16-6-5-15(29-16)18(25)21-9-14-10-23(19(26)28-14)13-3-1-12(2-4-13)22-7-8-27-11-17(22)24/h1-6,14H,7-11H2,(H,21,25) |
| Inchi Key | KGFYHTZWPPHNLQ-UHFFFAOYSA-N |
| SMILES | C1COCC(=O)N1C2=CC=C(C=C2)N3CC(OC3=O)CNC(=O)C4=CC=C(S4)Cl |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/Rivaroxaban.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Rivaroxaban-Xarelto-chemical-structure-S3002.gif |