TAK-715
TAK-715 is a p38 MAPK inhibitor for p38α with IC50 of 7.1 nM, 28-fold more selective for p38α over p38β, no inhibition to p38γ/δ, JNK1, ERK1, IKKβ, MEKK1 or TAK1. Phase 2.
| Trivial name | N/A |
| Catalog Number | S2928 |
| Molecular Formula | C29H33NO5 |
| CAS# | 303162-79-0 |
| Inchi | InChI=1S/C29H33NO5/c1-20-22(12-9-13-24(20)21-10-5-4-6-11-21)19-35-23-16-27(33-2)25(28(17-23)34-3)18-30-15-8-7-14-26(30)29(31)32/h4-6,9-13,16-17,26H,7-8,14-15,18-19H2,1-3H3,(H,31,32)/t26-/m0/s1 |
| Inchi Key | ZBOYJODMIAUJHH-SANMLTNESA-N |
| SMILES | CC1=C(C=CC=C1C2=CC=CC=C2)COC3=CC(=C(C(=C3)OC)CN4CCCCC4C(=O)O)OC |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/tak-715.html |
| Additional Information | https://file.selleck.cn/downloads/struct/TAK-715-chemical-structure-s2928.jpg |