TAK-715
TAK-715 is a p38 MAPK inhibitor for p38α with IC50 of 7.1 nM, 28-fold more selective for p38α over p38β, no inhibition to p38γ/δ, JNK1, ERK1, IKKβ, MEKK1 or TAK1. Phase 2.
| Trivial name | N/A |
| Catalog Number | S2928 |
| Molecular Formula | C24H21N3OS |
| CAS# | 303162-79-0 |
| Inchi | InChI=1S/C24H21N3OS/c1-3-21-27-22(18-11-7-8-16(2)14-18)23(29-21)19-12-13-25-20(15-19)26-24(28)17-9-5-4-6-10-17/h4-15H,3H2,1-2H3,(H,25,26,28) |
| Inchi Key | HEKAIDKUDLCBRU-UHFFFAOYSA-N |
| SMILES | CCC1=NC(=C(S1)C2=CC(=NC=C2)NC(=O)C3=CC=CC=C3)C4=CC=CC(=C4)C |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/tak-715.html |
| Additional Information | https://file.selleck.cn/downloads/struct/TAK-715-chemical-structure-s2928.jpg |