BAY 11-7082
BAY 11-7082 (BAY 11-7821) is a NF-κB inhibitor, inhibits TNFα-induced IκBα phosphorylation with IC50 of 10 μM in tumor cells. BAY 11-7082 inhibits ubiquitin-specific protease USP7 and USP21 with IC50 of 0.19 μM and 0.96 μM, respectively. BAY 11-7082 induces apoptosis and S phase arrest in gastric cancer cells.
| Trivial name | BAY 11-7821 |
| Catalog Number | S2913 |
| Molecular Formula | C10H9NO2S |
| CAS# | 19542-67-7 |
| Inchi | InChI=1S/C10H9NO2S/c1-9-3-5-10(6-4-9)14(12,13)8-2-7-11/h2-6,8H,1H3/b8-2+ |
| Inchi Key | DOEWDSDBFRHVAP-KRXBUXKQSA-N |
| SMILES | CC1=CC=C(C=C1)S(=O)(=O)C=CC#N |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/bay-11-7082-bay-11-7821.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s2913-bay-11-7082-chemical-structure.png |